Harnessing cell maturation

Dissecting circadian developmental control

Seeking a cure for diabetes

Welcome to the J-RAD Lab


We embrace diversity, equity, and inclusion. We strive to deliberately counteract unconscious bias and historical disenfranchisement by nurturing the diversity of our members, providing equitable access no matter race, ethnicity, gender, age, sexual orientation, neurocognitive and physical abilities, or religion, and fostering opportunities for people underrepresented in science.



We study how circadian rhythms shape cell development and maturation, using human stem cell- derived organoids as research models and as therapies for human diseases.



Our Team

Juan Rene Alvarez Domínguez, Ph.D.
Juan grew up in Guatemala, and went to school there and in Italy. He graduated from Princeton university with a B.A. in Molecular Biology, and from the Massachusetts Institute of Technology with a Ph.D. in Biology. He worked as an HHMI LSRF Fellow in the Melton Lab at Harvard University, studying the physiological maturation of pancreatic islets. His interests include regenerative medicine, circadian rhythms, and organoids. Outside of lab, Juan enjoys film, music, travel, skiing, and chess.
Sam Pollock, B.S.
Sam graduated from the University of Pittsburgh in 2017 with a degree in bioengineering and a minor in chemistry. He worked in the neuro-radiology department of the Children's Hospital of Pittsburgh for a year before joining the Peace Corps, serving in Guinea for two years as a math teacher. Sam's professional interests include genetics, neurology, epidemiology, imaging, and signals and systems. His personal interests include rock climbing, skiing, traveling, reading, and music.